Fish oil supplements have soared in popularity due to their abundant health benefits. Extracted from oily fish tissues, these supplements brim with Omega-3 fatty acids, specifically Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA). Since our bodies can't produce these essential fats, we must incorporate them into our diet or take them as supplements.

High-concentrated Omega-3 products, particularly those with concentrations over 90% per capsule like Lurky UltraPure Omega-3, offer distinct advantages. Here are a few reasons why they are essential:

 • Enhanced Bioavailability: High-concentration Omega-3 products can provide more active Omega-3 fatty acids in each dose, increasing bioavailability. This ensures that more of these beneficial compounds are available for absorption and use by your body, leading to potentially greater health benefits.

• Achieving Therapeutic Dosage: For specific health conditions, like high triglycerides, a high-dose Omega-3(EPA) supplement may be necessary. Lurky UltraPure Omega-3 with a higher concentration of Omega-3(EPA) per capsule makes it easier to achieve such therapeutic dosages without needing to consume large quantities of capsules.

• Ease and Adherence: The higher the Omega-3 concentration in a supplement, the fewer capsules you need to take to meet your daily recommended or prescribed intake. Lurky UltraPure Omega-3, with its optimal 1g capsule size, offers a solution for those who find swallowing pills challenging or have multiple supplements in their daily routine. This high-concentration formula allows you to attain the necessary therapeutic dosage without the inconvenience of consuming bulky capsules or large-volume dosages.

Effects on Cardiovascular Disease: Numerous studies underscore the relationship between EPA, an Omega-3 fatty acid, and heart health. It's well-documented that EPA can lower blood triglyceride levels, potentially mitigating heart disease risk. A standout study published in the New England Journal of Medicine in 2019 evidenced a 25% reduction in major adverse cardiovascular events in patients consuming a high-concentration, pharmaceutical-grade EPA supplement compared to a placebo group [1].

Effects on Reducing Blood Fats Levels: The American Heart Association, addressing triglycerides (TGs) and cardiovascular disease, recommends 2 to 4 g/day of EPA plus DHA for patients who need to lower TG levels. More recently, the Endocrine Society suggested that omega-3 fatty acids alone or in combination with statins could be considered a treatment option for patients with moderate-to-severe TG levels. Researchers found omega-3 fatty acids administered as fish oil supplements or as prescription could lower plasma TG levels by 25% to 34% when taking high strength of omega-3 for at least 2g/day. A meta-study also suggests that pure EPA might be a better choice since formulations that contain both EPA and DHA may lower TG levels, but they may also increase cholesterol levels [2].

Effects on Depression: Research accentuates the value of fish oil supplements rich in EPA, specifically those containing 100% EPA or at least 60% EPA, for managing major depression symptoms. Notably, these benefits become observable when the supplement is taken at dosages of up to 1~2 gram per day. Supplements primarily containing DHA didn't demonstrate the same effects, suggesting that a daily dose of our EPA-rich fish oil supplement could potentially help manage depression symptoms, reducing symptoms by around 10~30% [3],[4].

Anti-inflammatory Effects: Thanks to its anti-inflammatory properties, EPA is being explored for its potential benefits in inflammatory conditions like rheumatoid arthritis. Some studies suggest that fish oil supplements, rich in EPA and DHA, can alleviate joint pain and stiffness in rheumatoid arthritis patients [5].

Omega-3 fatty acids in fish oil exist in different forms, including triglyceride (TG), ethyl ester (EE), and re-esterified triglyceride (rTG). These forms have distinct bioavailability, affecting how well our body can absorb and utilize them.

Scientific consensus suggests the following order of bioavailability: rTG > TG > EE. While many Omega-3 product producers choose the EE form due to cost-effectiveness, Lurky UltraPure Omega-3 prioritizes absorption rates and bioavailability by choosing the rTG form, despite its higher production costs.

 Among these studies, one conducted by Dyerberg et al in 2010 [6] is probably one of the most cited regarding the varying bioavailability found in natural fish body oil (TG), rTG, and EE forms. This research indicates that the bioavailability of re-esterified triglycerides (rTG) was superior (124%) compared to natural fish oil, whereas the bioavailability from ethyl esters was inferior (73%) as shown in the graph below.

A rigorous, cross-over study highlighted the varying efficacies of different Omega-3 supplement forms in boosting blood Omega-3 levels and mitigating cardiovascular disease risk. In the study, 35 healthy subjects took each of four supplements: re-esterified triglyceride (rTG) fish oil, ethyl ester (EE) fish oil, phospholipid (PL) krill oil, and triglyceride (TG) salmon oil.

As seen in the graph below, the standout result was the concentrated rTG fish oil, which resulted in the highest increase in whole blood Omega-3 fatty acid levels and the most significant reduction in cardiovascular disease risk factors.[7]

Given these findings, Lurky UltraPure Omega-3, which harnesses the power of a high concentration of EPA in the highly bioavailable rTG form, is optimally positioned to support cardiovascular health. This study underscores the advantage of choosing Lurky UltraPure Omega-3 as a supplement, as it not only delivers a high concentration of vital Omega-3 fatty acids but also ensures they are readily absorbed and utilized by the body. By using the rTG form, Lurky UltraPure Omega-3 offers an effective solution in the journey to improve cardiovascular health.

• Experience Superior Absorption: Immerse in the advantage of our re-esterified Triglyceride (rTG) formula, scientifically proven to offer peak absorption, supercharging your system with all the goodness of Omega-3s.

• Bask in the Power of Concentrated EPA: Elevate your wellness routine with our robust concentration of Eicosapentaenoic Acid (EPA). Dive into a sea of benefits from heart health to mental wellbeing, to inflammation control - it's health transformation in a capsule!

• Cardiovascular Health Enhancer: Scientific studies highlight the unmatched potential of our concentrated rTG fish oil, which significantly increases blood Omega-3 levels and reduces cardiovascular disease risk. Consider it your heart's best ally!

• Purity and Quality Assurance: Our fish oil supplement undergoes rigorous testing to ensure purity and quality. We prioritize your health and ensure our product is free from contaminants.

• Sustainable Sourcing: We are committed to sustainability. Our fish oil is sourced responsibly, ensuring minimal impact on marine ecosystems.
  
  Choose Lurky UltraPure Omega-3 - where quality, efficacy, and sustainability coalesce to shape a healthier, happier you!

[1] Basha, Ma. (2019) ‘Cardiovascular risk reduction with icosapent ethyl for Hypertriglyceridemia’, Journal of the Practice of Cardiovascular Sciences, 5(1), p. 44. doi:10.4103/jpcs.jpcs_16_19.

[2] Bradberry, J. C., & Hilleman, D. E. (2013). Overview of omega-3 Fatty Acid therapies. P & T : a peer-reviewed journal for formulary management, 38(11), 681–691.

[3] Grosso, G. et al. (2014) ‘Role of omega-3 fatty acids in the treatment of depressive disorders: A comprehensive meta-analysis of randomized clinical trials’, PLoS ONE, 9(5). doi:10.1371/journal.pone.0096905.

[4] Liao, Y. et al. (2019) ‘Efficacy of omega-3 pufas in depression: A meta-analysis’, Translational Psychiatry, 9(1). doi:10.1038/s41398-019-0515-5.

[5] Crupi, R. and Cuzzocrea, S. (2022) ‘Role of EPA in inflammation: Mechanisms, effects, and clinical relevance’, Biomolecules, 12(2), p. 242. doi:10.3390/biom12020242.

[6] J. Dyerberg, H.O. Bang. Plasma Lipid and lipoprotein pattern in Greenlandic West-Coast Eskimos, The Lancet, vol. 297, issue7710: 1143-1146]

[7] Laidlaw et al. A randomized clinical trial to determine the efficacy of manufacturers’ recommended doses of omega-3 fatty acids from different sources in facilitating cardiovascular disease risk reduction. Lipids in Health and Disease (2014)